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  • Title: Progesterone-induced DNA polymerase activity in full-grown oocytes of Xenopus laevis (1).
    Author: Grippo P, Locorotondo G, Taddei C.
    Journal: J Exp Zool; 1977 Apr; 200(1):143-8. PubMed ID: 859007.
    Abstract:
    DNA polymerase activity increases in full-grown oocytes of Xenopus laevis during in vitro progesterone-induced maturation. This increase is inhibited by cycloheximide. The presence of the oocyte's nucleus (germinal vesicle) seems essential for the induction of this increase: in previously enucleated oocytes, the level of DNA polymerase activity does not change during progesterone treatment. Furthermore, a new form of DNA polymerase is detectable by DEAE chromatography in in vitro matured oocytes.
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