These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The effect of chronic ethanol administration on arachidonyl transfer to 1-acyl-glycerophosphorylcholine in rat brain synaptosomal fraction.
    Author: Sun GY, Creech DM, Corbin DR, Sun AY.
    Journal: Res Commun Chem Pathol Pharmacol; 1977 Apr; 16(4):753-6. PubMed ID: 860087.
    Abstract:
    Enzymatic transfer of arachidonate to synaptosomal diacyl-GPC in a group of rats (n=14) administered 30% ethanol by intragastric intubation for 21 days was 24% higher than controls (n=5) (P less than 0.05). No apparent difference in enzymic activity was observed with respect to different periods of withdrawal (8-24 hrs). The acyl transferase activity in another group of rats (n=5) which were given 15% ethanol as the sole drinking source for 13 months was 58% higher than controls (P less than 0.025). The increase in acyl transferase activity with respect to the two types of chronic ethanol administration may be due to an adaptive mechanism in brain to facilitate the increase in membrane transport activities which are known to occur under the influence of ethanol.
    [Abstract] [Full Text] [Related] [New Search]