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  • Title: Insecticide solvents: interference with insecticidal action.
    Author: Brattsten LB, Wilkinson CF.
    Journal: Science; 1977 Jun 10; 196(4295):1211-3. PubMed ID: 860135.
    Abstract:
    Several commercial solvent mixtures commonly used as insecticide carriers in spray formulations increase by more than threefold the microsomal N-demethylation of p-chloro N-methylaniline in midgut preparations of southern army-worm (Spodoptera eridania) larvae exposed orally to the test solvents. Under laboratory conditions, the same solvent mixtures exhibit a protective action against the in vivo toxicity of the insecticide carbaryl to the larvae. The data are discussed with respect to possible solvent-insecticide interactions occurring under field conditions and, more broadly, to potential toxicological hazards of these solvents to humans.
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