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  • Title: Condyloma acuminatum and squamous carcinoma of the vulva.
    Author: Rhatigan RM, Saffos RO.
    Journal: South Med J; 1977 May; 70(5):591-4. PubMed ID: 860150.
    Abstract:
    Reported is the association of condyloma acuminatum and squamous carcinoma of the vulva in three cases and condyloma followed by squamous dysplasia in a fourth case. This association has previously been reported in both male and female genitalia and in the perianal area. In our four cases, cancer or squamous dysplasia followed long-standing or extensive condyloma, but there was no evidence of transformation from condyloma to carcinoma. In one of the cases, areas of squamous dysplasia occurred in multiple foci within a large condyloma. It is not known whether condyloma acuminatum is a precancerous skin lesions, but long-standing or extensive condylomas should alert one to the possibility of carcinoma.
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