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  • Title: The transverse location of the fluorescent probe trans-parinaric acid in lipid bilayers.
    Author: Castanho M, Prieto M, Acuña AU.
    Journal: Biochim Biophys Acta; 1996 Mar 13; 1279(2):164-8. PubMed ID: 8603083.
    Abstract:
    The transverse location of trans-parinaric acid in spherical vesicles made up from dipalmitoylphosphatidylcholine has been investigated by the differential quenching of the probe fluorescence by 5- and 16-doxylstearic acid derivatives. The quenching data are interpreted in terms of a local fluorophore concentration factor. In this way it was found that the polyene of t-PnA is located within the inner part of the bilayer (presumably aligned with the bilayer lipids), both in the gel and in the liquid crystalline phases.
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