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  • Title: [The use of the screening of maternal serum factors for the prenatal diagnosis of fetal developmental defects and chromosomal diseases].
    Author: Arbuzova SB, Nikolenko MI.
    Journal: Tsitol Genet; 1995; 29(4):44-7. PubMed ID: 8604526.
    Abstract:
    The association of the levels of alpha-fetoprotein and chorionic gonadotropin with congenital developmental defects and chromosomal abnormalities of fetus was studied. The correlation of elevated level of alpha-fetoprotein with defects of neuraxis, kidney and abdominal wall of fetus was shown. These data are used for screening of women with a high risk for Down's syndrome and other chromosomal abnormalities.
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