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  • Title: A randomised controlled trial of early versus delayed use of amniotomy and oxytocin infusion in nulliparous labour.
    Author: Cammu H, Van Eeckhout E.
    Journal: Br J Obstet Gynaecol; 1996 Apr; 103(4):313-8. PubMed ID: 8605126.
    Abstract:
    OBJECTIVE: To compare routine amniotomy and early intravenous oxytocin (active management of labour) with a more selective use of amniotomy and oxytocin in women in true labour who received comparable continuous supportive midwifery care. DESIGN: Randomised controlled trial of nulliparous clinic patients in spontaneous labour at term. SETTING: Labour and delivery ward of a university teaching hospital. PARTICIPANTS: Three hundred and six parturients: 152 received active management of labour; 154 were more selectively managed. INTERVENTIONS: 1. Active management: early amniotomy, early use of oxytocin. 2. Selective intervention management: no routine amniotomy and more selective use of oxytocin. OUTCOME MEASURES: Use of oxytocin and amniotomy. Labour duration, mode of delivery. RESULTS: Maternal characteristics were comparable in both groups. Amniotomy was more often performed (91% versus 57%, P <0.01) and oxytocin more often used (53% versus 27%, P < 0.01) in the active management group. The first stage of labour, however, was only shortened by half an hour in the active management group (254 min versus 283 min, P = 0.087). Caesarean section rate (3.9% versus 2.6%), spontaneous vaginal delivery rate (78% versus 79%) and neonatal outcome were not significantly different between groups. CONCLUSION: Within a set-up of strict labour diagnosis and supportive midwifery care, routine amniotomy and early use of oxytocin offered no advantage over a more selective use of amniotomy and oxytocin in terms of mode of delivery and labour duration.
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