These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Different immunosuppressive effects of liposomal FK506 in liver and kidney transplantation.
    Author: Ko S, Nakajima Y, Kanehiro H, Horikawa M, Yoshimura A, Kido K, Taki J, Aomatsu Y, Kin T, Yagura K, Ohyama T, Ohashi K, Yamada T, Nakano H.
    Journal: Transplant Proc; 1996 Apr; 28(2):1066-8. PubMed ID: 8623229.
    Abstract:
    The efficacy of liposomal FK506 was compared between a canine liver transplantation model and a canine kidney transplantation model. The present study revealed that liposomal FK506 increased immunosuppressive efficacy of FK506 in liver transplantation but decreased in kidney transplantation. Because liposomal FK506 increased FK506 levels in the liver and spleen, and decreased FK506 levels in the kidney, it was suggested that enhanced immunosuppressive efficacy in liver transplantation should be attributed to the local immunosuppressive effects in the hepatic allograft rather than effective suppression of splenocyte activity.
    [Abstract] [Full Text] [Related] [New Search]