These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Cocaine's effect on plasma oxytocin concentrations in the baboon during late pregnancy.
    Author: Morgan MA, Honnebier MB, Mecenas C, Nathanielsz PW.
    Journal: Am J Obstet Gynecol; 1996 Mar; 174(3):1026-7. PubMed ID: 8633630.
    Abstract:
    OBJECTIVE: The hypothesis for this investigation was that intravenous cocaine would result in an elevation of maternal plasma oxytocin levels in the baboon during late pregnancy. STUDY DESIGN: Five gravid chronically instrumented baboons had timed arterial blood samples obtained before and after an intravenous bolus cocaine infusion at least 5 days after surgery. Plasma oxytocin concentrations were measured by specific radioimmunoassays, and baseline samples were compared with postcocaine samples. RESULTS: The plasma oxytocin concentrations were significantly elevated at all sampling times after the 1.0 mg/kg cocaine dose (p<0.05). CONCLUSION: The increased oxytocin concentration after cocaine use may be responsible for the increased incidence of preterm labor.
    [Abstract] [Full Text] [Related] [New Search]