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  • Title: Amphotericin B for the treatment of localized subcutaneous phycomycosis in the horse.
    Author: McMullan WC, Joyce JR, Hanselka DV, Heitmann JM.
    Journal: J Am Vet Med Assoc; 1977 Jun 01; 170(11):1293-8. PubMed ID: 863774.
    Abstract:
    Amphotericin B was used systemically or locally, or both, in the treatment of localized subcutaneous phycomycosis in horses. In 8 of 10 cases, the results were satisfactory. Intravenous treatment was well tolerated at an average starting daily dosage of 0.38 mg/kg, increasing up to as high as 1.47 mg/kg. It was concluded that the ideal treatment regimen would include early surgical removal of the lesion followed by daily intravenous and topical administration of amphotericin B, with periodic extirpation of small necrotic tracts as necessary.
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