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  • Title: Long-term salvage treatment by cyclosporin in refractory autoimmune haematological disorders.
    Author: Emilia G, Messora C, Longo G, Bertesi M.
    Journal: Br J Haematol; 1996 May; 93(2):341-4. PubMed ID: 8639426.
    Abstract:
    We report on long-term treatment (13-62 months) with cyclosporin A (CyA) in eight patients with autoimmune haematological disorders, resistant to all usual therapies. Three patients had an autoimmune haemolytic anaemia (AHA); four an idiopathic thrombocytopenic purpura (ITP), and one an Evans syndrome. All patients were responsive: six achieved complete remission and two partial remission. The side-effects were moderate and transient. The majority of surviving patients remain dependent on continued drug administration. The CyA appears to be recommendable as a salvage treatment in life-threatening, resistant autoimmune haematological diseases.
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