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  • Title: An improved procedure for the synthesis of glycine and taurine conjugates of bile acids.
    Author: Tserng KY, Hachey DL, Klein PD.
    Journal: J Lipid Res; 1977 May; 18(3):404-7. PubMed ID: 864329.
    Abstract:
    Glycine and taurine conjugates of 5beta-cholanic acids have been synthesized using improved procedures based on the peptide coupling reagent, N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline. The conjugates are obtained in chromatographically pure form in yields higher than 90%. The use of this procedure in the large scale preparation of cholyl[1,2-13C2]glycine is described.
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