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  • Title: Evidence for a model ancestral viroid.
    Author: Bussière F, Lafontaine D, Côté F, Beaudry D, Perreault JP.
    Journal: Nucleic Acids Symp Ser; 1995; (33):143-4. PubMed ID: 8643352.
    Abstract:
    The generation of a phylogenetic tree of viroids and viroid-like plant satellite RNAs via computer analysis, coupled with several conspicuous biochemical characteristics of the rolling circle replication of these RNAs -including both self-cleavage and self-ligation- leads us to propose the peach latent mosaic viroid (PLMVd) as a current "living fossil" dating from a precellular world. Incorporated within this proposal is a revised mechanism of PLMVd rolling circle replication which requires a minimal protein involvement.
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