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  • Title: Reverse use dependence of human ventricular repolarization by chronic oral sotalol in monophasic action potential recordings.
    Author: Shimizu W, Kurita T, Suyama K, Aihara N, Kamakura S, Shimomura K.
    Journal: Am J Cardiol; 1996 May 01; 77(11):1004-8. PubMed ID: 8644624.
    Abstract:
    Reverse use dependence of action potential duration and effective refractory period by chronic oral sotalol was demonstrated by monophasic action potential recordings in the human ventricle. There were no changes of the QRS duration over the cycle length, indicating that sotalol had no sodium channel blocking effects.
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