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Title: Synthesis and in vitro antitumor activity evaluation of 9-substituted 1,2,3,4-tetrahydrocarbazoles. Author: Grasso S, Molica C, Monforte AM, Monforte P, Zappalà M, Rizzo M. Journal: Farmaco; 1996 Apr; 51(4):269-74. PubMed ID: 8645414. Abstract: A series of 9-acetamido-1,2,3,4-tetrahydrocarbazoles (2) and 9-(aminoalkyloxyethyl)-1,2,3,4-tetrahydrocarbazoles (4) were prepared and tested for their in vitro antitumor activity. Compounds 4 are highly cytotoxic in almost all subpanel cell lines when tested at 10(-4) M, but showed a weak activity at the lowest concentrations employed.[Abstract] [Full Text] [Related] [New Search]