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  • Title: Cloning and characterization of cDNAs coding for heavy and light chains of a monoclonal antibody (MabB23) specific for human plasma apolipoprotein B-100.
    Author: Kwak JW, Choi BK, Lee DI, Kang YK, Seo YG, Cho WK, Han MH.
    Journal: Gene; 1996 Mar 09; 169(2):237-9. PubMed ID: 8647454.
    Abstract:
    We have determined the nucleotide sequences encoding the heavy and light chains of the Fab fragment of murine monoclonal antibody MabB23(gamma2b,lambda), which is specific for human plasma apolipoprotein B-100 of low-density lipoproteins. The sequence analyses revealed that the variable regions of the heavy and light chains are members of mouse heavy-chain subgroup I(B) and lambda light-chain, respectively. A few unusual amino acids in the framework and constant regions of the heavy-chain were also noticed.
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