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  • Title: [Septicemia in children treated with exchange transfusions because of hemolytic disease of the newborn].
    Author: Kordyasz E.
    Journal: Pediatr Pol; 1995 Sep; 70(9):733-7. PubMed ID: 8657505.
    Abstract:
    Clinical signs and laboratory test results were analyzed in 70 neonates (42 boys and 28 girls) hospitalized because of neonatal haemolytic disease who were treated with exchange transfusion and later developed septicaemia. Serological Rh-D incompatibility was diagnosed in 11 children, ABO incompatibility in 59. Signs of infection appeared between days 1 and 7 after transfusion. Pneumonic signs and diarrhoea dominated clinically in 45 newborns, skin abscesses were observed in 10, osteomyelitis in 4. Septic shock occurred in 7. Gram-negative bacteria predominated (52.85%). A significant diagnostic value of the following was found (chi2): granulocytic band forms (expressed as percentages > or = 0.10, a neutrophil index > 0.2 and toxic granulations in neutrophils. These results were obtained in the early, asymptomatic stage of infection, i.e. before the exchange transfusion was performed. The importance of the presence of risk factors, not exchange transfusion per se, is stressed.
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