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  • Title: Multiple subpial transection for Landau-Kleffner syndrome.
    Author: Buelow JM, Aydelott P, Pierz DM, Heck B.
    Journal: AORN J; 1996 Apr; 63(4):727-9, 732-5, 737-9; quiz 741-4. PubMed ID: 8660018.
    Abstract:
    Landau-Kleffner syndrome (LKS) is an acquired epileptic aphasia caused by a lesion in the speech centers of the cerebral cortex during a critical period of childhood development. Characteristics of LKS include language deterioration, seizure disorders, and severe electroencephalogram abnormalities. Multiple subpial transection (MST) is a surgical procedure that eliminates seizure activity in the cerebral cortex while preserving the child's normal cortical functions of speech, movement, primary sensation, and memory. This article presents a summary of clinical studies on LKS and discusses the diagnosis of LKS, traditional medical treatments, patient selection for MST procedures, and perioperative care of children undergoing MST procedures.
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