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  • Title: Growth rate of lung metastases and S-phase fraction as determined by flow cytometry from the primary tumour in 25 patients with bone or soft-tissue sarcomas.
    Author: Blomqvist C, Huuhtanen R, Pan Y, Wiklund T, Tarkkanen M, Virolainen M, Tribukait B.
    Journal: Br J Cancer; 1996 Jun; 73(12):1556-9. PubMed ID: 8664129.
    Abstract:
    A significant correlation (r = -0.48) was found between the logarithm of the S-phase fraction of the primary tumour (SPF) and the logarithm of the doubling time of lung metastases (T2). The estimated median cell loss factor was 88% (range 35-99%).
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