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  • Title: [Clinicopharmacological case report (3). Drug-induced angioedema].
    Author: Kind B, Fattinger K, Krähenbühl S, Meier-Abt PJ.
    Journal: Praxis (Bern 1994); 1996 Apr 23; 85(17):567-9. PubMed ID: 8668896.
    Abstract:
    We report the case of a patient with an angioedema during therapy with enalapril and tramadol. The most likely cause of the adverse effect if the ACE-inhibitor enalapril. A rechallenge with the ACE-inhibitor is dangerous and should not be performed. Because of its potential risks, further treatment with ACE-inhibitors should be avoided in all patients with ACE-inhibitor-induced angioedema. Possible therapeutic alternatives include diuretics, beta-blocking agents, calcium antagonists and also angiotensin II receptor antagonists.
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