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  • Title: Radioimmunoassay for abnormal hemoglobins.
    Author: Garver FA, Baker MB, Jones CS, Gravely M, Altay G, Huisman TH.
    Journal: Science; 1977 Jun 17; 196(4296):1334-6. PubMed ID: 867032.
    Abstract:
    A sensitive and specific radioimmunoassay has been developed for the identification or quantification of the human hemoglobin variants S, C, D-Los Angeles, E, G Philadelphia, Russ, O Arab, Beograd, J Paris I, G San Jose, Q Iran, Korle Bu, and F Malta I. In the immunoassay, monospecific antibody preparations are used which recognize the single amino acid substitution in the variant polypeptide chail and do not cross-react with normal hemoglobins or hemoglobin variants containing a different amino acid exchange at the same position.
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