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  • Title: [Age and changes in the concentration of dicarboxylic amino acids and GABA in different portions of the dog cerebral cortex and cerebellum].
    Author: Agaev TM, Ifraimova ZN.
    Journal: Ukr Biokhim Zh; 1977; 49(2):27-9. PubMed ID: 867535.
    Abstract:
    The content of dicarboxylic amino acids lowers with age in all the structures of cerebral cortex and cerebellum under study when calculating per I g of fresh tissue and 100 mg of protein. The greatest decrease in the amount of glutaminic and aspartic acids is found in the parietal region at the senile age. The content of GABA in all the brain structures of three-year dogs is significantly higher than in the one-year dogs and at the senile age it is somewhat lower as compared to the three-year animals when calculating per 1 g of fresh tissue, the degree of the decrease in all the studied regions being practically the same.
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