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  • Title: [A case of recurrent breast carcinoma with metastatic foci in the lung and pleura treated successfully with biochemical modulation of 5-fluorouracil by low-dose cisplatin].
    Author: Oura S, Sakurai T, Yoshimura G, Tamaki T, Umemura T.
    Journal: Gan To Kagaku Ryoho; 1996 Jul; 23(8):1069-71. PubMed ID: 8687224.
    Abstract:
    A 65-year-old female received nipple preserved total glandectomy for breast carcinoma. A 250 mg dose of epirubicin was administered as an adjuvant. After a three-year disease-free interval, breast carcinoma recurred in the lung and pleura. We then used biochemical modulation of 5-fluorouracil by low-dose cisplatin. One course of biochemical modulation resulted in eighty-three percent tumor regression and complete disappearance of the pleural effusion for over six months.
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