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  • Title: [Results of postoperative cervical node irradiation in carcinoma of the pharyngo-larynx. A study of the cooperative group of radiotherapists].
    Author: Hoffstetter S, Malissard L, N'Guyen TD, Panis X, Jung GM, Bachaud JM, Prevost B, Quint R, Chaplain G, Eschwège F, Rambert P, Fleury-Touzeau F.
    Journal: Bull Cancer Radiother; 1996; 83(2):86-9. PubMed ID: 8688224.
    Abstract:
    From 1981 to 1985, 428 patients presenting with an epidermoid carcinoma of the hypopharynx and/or larynx were treated with a curative intent by surgical resection and postoperative irradiation. Two-thirds of the tumours were T3 and 60% of patients presented with a clinical node involvement. The rates of local failure were 8%, 18% and 13%, respectively, for cancers of the larynx, of the piriform sinus and of the posterior wall; the rates of regional failure were 8%, 23% and 13%, respectively. There is no head and neck site with either a high or low risk of recurrence after resection, but the capsular rupture remains a factor of poor prognosis. The survival rate at 5 years of the whole series is 38%, for laryngeal localisation it reaches 62%. The risk of metastases is related to the node involvement and the interval between surgery and irradiation.
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