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  • Title: A case of small cell carcinoma of the lung associated with hypertrophic pulmonary osteoarthropathy.
    Author: Fujishita T, Mizushima Y, Yoshida Y, Kitagawa M, Kobayashi M.
    Journal: Tumori; 1996; 82(3):259-61. PubMed ID: 8693607.
    Abstract:
    A 73-year-old man had complained of painful swelling in the upper and lower extremities for several months before detection of small cell lung carcinoma. A bone scan showed abnormal symmetrical accumulations in the extremities, but periosteal proliferation was not demonstrated by X-ray. When a complete remission was obtained by chemoradiotherapy, the joint manifestation also subsided completely. In almost all reported cases, hypertrophic pulmonary osteoarthropathy was observed in all patients with non-small cell lung carcinoma. To our knowledge, this is the first case report of hypertrophic pulmonary osteoarthropathy associated with small cell lung carcinoma published in the English literature.
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