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  • Title: Myocardial necrosis and QRS complex changes in the ischemia-reperfusion setting in a baboon model.
    Author: Premaratne S, LaPenna WF, Siu B, McNamara JJ.
    Journal: Coron Artery Dis; 1995 Nov; 6(11):897-9. PubMed ID: 8696535.
    Abstract:
    BACKGROUND: This study was performed in attempt to draw a correlation between the percentage of myocardial infarction across the left ventricular wall and changes in the QRS complex in the epicardial ECG in a primate model of ischemia-reperfusion injury. METHODS: Myocardial infarction was induced in six baboons by ligating the left anterior descending coronary artery for 2h. Using ECG leads, the presence of Q and R waves was recorded along with their associated left ventricular wall thickness. RESULTS AND CONCLUSIONS: The results indicate that Q-wave development and R-wave loss can be correlated with depth of infarct.
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