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  • Title: [Inhibition of ornithine decarboxylase activity and epidermal papilloma in mice by beta-carotene].
    Author: Tan A, Wu K, Huang M.
    Journal: Zhonghua Yu Fang Yi Xue Za Zhi; 1995 Nov; 29(6):360-2. PubMed ID: 8697943.
    Abstract:
    Anticarcinogenic action of beta-carotene was analyzed with determination of ornithine decarboxylase (ODC) activity induced by TPA and a two-stage model of skin papilloma-genesis in mice. Results showed increase of ODC activity induced by TPA could be significantly inhibited, onset of tumor postponed, and number of tumor foci decreased by beta-carotene. It suggested beta-carotene had an obvious chemoprophylactic effect on tumor.
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