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  • Title: Increased frequency of HLA-Cw3 and HLA-Dw4 in rheumatoid arthritis.
    Author: McMichael AJ, Sasazuki T, McDevitt HO, Payne RO.
    Journal: Arthritis Rheum; 1977 Jun; 20(5):1037-42. PubMed ID: 869952.
    Abstract:
    Thirty-nine patients with rheumatoid arthritis were HLA typed for the full range of A and B locus specificities and for Cw3 and Dw4. HLA-Dw4 was significantly more frequent in patients (36%) than in controls (13%). The frequency of Cw3 was also increased, probably because this allele is in linkage disequilibrium with Dw4.
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