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  • Title: Thermodynamics of the isothermal interaction of beta-lactoglobulin with guanidinium chloride and urea.
    Author: Lapanje S, Lunder M, Vlachy V, Skerjanc J.
    Journal: Biochim Biophys Acta; 1977 Apr 25; 491(2):482-90. PubMed ID: 870064.
    Abstract:
    A thermodynamic study of the isothermal interaction of beta-lactoglobulin with guanidinium chloride and urea has been performed. Enthalpies of interaction of the two denaturants have been obtained by calorimetric measurements, and the free energy of interaction calculated from previously determined preferential binding of denaturants. In separate dilatometric experiments the volume changes accompanying the interaction of guanidinium chloride with beta-lactoglobulin have also been determined.
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