These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of hemodynamic changes on taurine release from posterior hypothalamus of freely moving rats.
    Author: Guo LJ, Athineos P.
    Journal: Zhongguo Yao Li Xue Bao; 1995 Sep; 16(5):405-8. PubMed ID: 8701754.
    Abstract:
    AIM: To study the effects of blood volume and vascular resistance on taurine release. METHODS: We used push-pull superfusion technique in the posterior hypothalamus of conscious freely moving rats. Taurine was determined in the superfusate by HPLC with fluorescence detection following automatic precolumn o-phthaldialdehyde (OPA) derivatization. RESULTS: Hypervolemia increased the release of taurine in the hypothalamus. Intravenous infusion of levarterenol (3 micrograms kg-1 min-1) elicited a pronounced pressor response and an increase in the release of taurine. Conversely, a controlled hemorrhagic hypotension or iv infusion of nitroprusside (30 micrograms kg-1 min-1) elicited a hypotension and a decrease in the release of taurine from the posterior hypothalamus. CONCLUSION: In the posterior hypothalamus, taurine might play an important role in central blood pressure regulation.
    [Abstract] [Full Text] [Related] [New Search]