These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Expressions of preproenkephalin mRNA during electroacupuncture analgesia enhanced by fenfluramine.
    Author: Li XY, Zhu CB, Zhu YH, Xu SF.
    Journal: Zhongguo Yao Li Xue Bao; 1995 Sep; 16(5):431-4. PubMed ID: 8701761.
    Abstract:
    AIM: To study the changes of preproenkephalin (PPE) mRNA in rat brain in response to electroacupuncture (EA) combined with fenfluramine (Fen), a releaser of 5-HT. METHODS: In situ hybridization histochemistry technique was used to observe the expression of PPE mRNA in rat brain during EA analgesia potentiated by Fen. RESULTS: The greatest relative increase of PPE mRNA was seen in lumbar spinal cord (laminae I & II), nucleus raphe magnus, dorsal raphe nucleus, periaqueductal gray, interpeduncular nucleus, preoptic lateral area, amygdala nucleus and caudate-putamen (P < 0.01, vs NS + EA). Moderate increases were found in lateral septal, preoptic medial area, hypothalamus ventromedial nucleus, lumbar spinal laminae III & IV (P < 0.05, vs NS + EA). Thalamus showed no statistical significant change in PPE mRNA. CONCLUSION: The enhancing of PPE mRNA in relative brain nuclei is involved in potentiating action of Fen on EA.
    [Abstract] [Full Text] [Related] [New Search]