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  • Title: Hyponatremia and hypernatremia.
    Author: Friedler RM, Koffler A, Kurokawa K.
    Journal: Clin Nephrol; 1977 Apr; 7(4):163-72. PubMed ID: 870270.
    Abstract:
    The concentration of serum sodium is determined by the external balance of water. Hyponatremia occurs when total body water is in excess of sodium, and hypernatremia develops when body water is relatively decreased in relation to sodium. Both disorders may be present in patients with various disease states in which total body sodium is either decreased, normal or increased. The symptomatology in both disorders is related to the disturbance in central nervous system due to brain edema in patients with hyponatremia and brain dehydration, and cerebrovascular hemorrhages in patients with hypernatremia. The treatment of hypo and hypernatremia is achieved by correcting the abnormalities in body water content.
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