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  • Title: The effect of vinblastin and vincristin on single nerve fibres.
    Author: Mitolo-Chieppa D.
    Journal: Experientia; 1977 Mar 15; 33(3):366-7. PubMed ID: 870334.
    Abstract:
    The perfusion of the node of Ranvier with vinblastin or vincristin reduces the amplitude of the action potential within a few seconds. Vincristins is 10fold more active than vinblastin. Upon withdrawal, the effect is promptly reversible and its is antagonized by acetylcholine.
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