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  • Title: [The effect of new synthetic prostanoids on the indices of the blood coagulation system].
    Author: Petrukhina GN, Makarov VA, Freĭmanis IaF, Lozha EV, Sirotenko AV.
    Journal: Eksp Klin Farmakol; 1995; 58(5):37-40. PubMed ID: 8704588.
    Abstract:
    In the experiments on rabbits it was shown, that the administration of prostanoids IOS 3933 caused a reduction of ADP- and collagen induced platelet aggregation, platelet adhesion to collagen and elevation of t-PA level. This prostanoid prevented both a decrease in platelet count and reduction of AT III activity, but did not affect the protein C level during thromboplastin infusion.
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