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  • Title: [The effect of antidepressants on the catecholamine content of the rat hypothalamus and adrenals].
    Author: Arushanian EB, El'bek'ian KS.
    Journal: Eksp Klin Farmakol; 1995; 58(6):14-6. PubMed ID: 8704602.
    Abstract:
    Chronic administration of depressants of various classes in rats and a single administration of reserpine result in changes in catecholamine exchange in both hypothalamus and adrenal glands. Antidepressants prevent from a sharp decrease in level of hypothalamic dofamine, induced with reserpine. The importance of central dofaminergic mechanisms for specific effect of compounds is emphasized.
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