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  • Title: Polymorphism of indomethacin. Part II. Identification and rapid determination of polymorphic forms of indomethacin by IR spectrometry.
    Author: Spychala S, Butkiewicz K, Pakula R, Pichnej L.
    Journal: Pol J Pharmacol Pharm; 1977; 29(2):157-60. PubMed ID: 870887.
    Abstract:
    A procedure is described, which make it possible to determine the content of individual polymorphic forms of indomethacin in their mixture by IR spectrometry. IR spectra recorded in the range of 1600--1800 cm-1 have been used in the determinations. The method is especially useful for analytical control of the technological process of preparing the most pharmacologically active-gemma-form of indomethacin.
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