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  • Title: Management of prolonged hypoglycaemia in Beckwith's syndrome.
    Author: Moncrieff MW, Lacey KA, Malleson PN.
    Journal: Postgrad Med J; 1977 Mar; 53(617):159-61. PubMed ID: 870893.
    Abstract:
    A new-born baby with Beckwith's syndrome had severe hypoglycaemia, and was treated with glucagon and prednisone. Treatment was stopped at 1 month of age and his blood glucose levels were satisfactory for the ensuing 6 weeks. However, at 10 weeks of age, he had a hypoglycaemic convulsion and required large doses of diazoxide and prednisone for the next 2 months to maintain the blood glucose above 40 mg/100 ml. Insulin excretion was raised until he was 4 months old. Cases of Beckwith's syndrome which develop hypoglycaemia, should be treated with diazoxide and corticosteroids until insulin excretion is normal.
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