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  • Title: Ginsenoside Rh4, a genuine dammarane glycoside from Korean red ginseng.
    Author: Baek NI, Kim DS, Lee YH, Park JD, Lee CB, Kim SI.
    Journal: Planta Med; 1996 Feb; 62(1):86-7. PubMed ID: 8720394.
    Abstract:
    A genuine glycoside, named ginsenoside Rh4, was isolated from Korean red ginseng (Panax ginseng C. A. Meyer) through repeated column chromatography, and its chemical structure was established to be 6-O-beta-D-glucopyranosyldammar-20(22),24-diene-3 beta,6 alpha,12 beta-triol by spectral and chemical methods. The stereochemistry of a double bond at C-20(22) of ginsenoside Rh4 was characterized as (E) from a NOESY experiment in the 1H-NMR of the aglycone. Cytotoxic activities of ginsenoside Rh4 and its aglycone against cancer cell lines were evaluated by use of the SRB method.
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