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  • Title: [pS2 protein and breast cancer].
    Author: Torre EA, Fulco RA.
    Journal: Minerva Ginecol; 1995 Dec; 47(12):553-6. PubMed ID: 8720977.
    Abstract:
    pS2 is a small protein (7000 daltons) that is prevalently expressed in human breast cancer positive for estrogen receptors: protein is, in fact, induced by estrogen stimulation. Studies indicate that pS2 protein is a marker for hormone-dependent breast tumors and that its expression is helpful in the prognosis. The presence of pS2, in fact, besides being associated in 96% of the cases to the positivities for estrogen receptors, is associated with longer overall, and disease free, survival. The pS2 protein is also expressed in normal stomach mucosa; its physiological function is unknown.
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