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  • Title: BUdR as a tracer of the possible mutagenic activity of Pb++ in human lymphocyte cultures.
    Author: Stella M, Rossi R, Martinucci GB, Rossi G, Bonfante A.
    Journal: Biochem Exp Biol; 1978; 14(3):221-31. PubMed ID: 87210.
    Abstract:
    The method of SCE was used as an indicator of the possible mutagenic activity of lead acetate in in vitro cultures of human lymphocytes. After determining the optimal concentration of BUdR, the cultures were treated with increasing doses of the metal. The negative results obtained with this method led us to examine other parameters, in particular the classical cytogenetic aberrations.
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