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  • Title: Synthesis and antimicrobial activity of benzo[a]dihydrocarbazole and benzotetrahydrocyclohept[1,2-b]indole derivatives.
    Author: Macchia M, Manera C, Nencetti S, Rossello A, Broccali G, Limonta D.
    Journal: Farmaco; 1996 Jan; 51(1):75-8. PubMed ID: 8721766.
    Abstract:
    A certain number of benzodihydrocarbazoles and benzotetrahydrocycloheptindoles were synthesized and tested for their antimicrobial activity. Compounds substituted on the nitrogen of the tetracyclic systems with a dimethylaminopropyl chain showed an antibacterial activity directed almost exclusively towards Gram-positive bacteria, while their N-unsubstituted analogs were completely inactive.
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