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Title: Renal function after high-dose urography in patients with chronic renal insufficiency. Author: Milman N, Gottlieb P. Journal: Clin Nephrol; 1977 Jun; 7(6):250-4. PubMed ID: 872463. Abstract: Renal function was assessed by frequent recordings of Ccr and serum creatinine in 22 patients with chronic renal failure before and after high-dose urography. Urography was followed by a significant, moderate and transient decrease in Ccr which was maximal on the second day; at the same time a significant increase in serum creatinine was observed which was maximal on the fourth day after urography. In all but two patients, Ccr and serum creatinine returned to pre-urographic levels within the next two weeks. Possible causes of the deleterious effects of the contrast media on the kidneys are discussed.[Abstract] [Full Text] [Related] [New Search]