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  • Title: Dicentric Y chromosome without evidence of mosaicism in an azoospermic male.
    Author: Sasagawa I, Ishigooka M, Kato T, Hayami S, Hashimoto T, Nakada T.
    Journal: Scand J Urol Nephrol; 1996 Feb; 30(1):75-6. PubMed ID: 8727871.
    Abstract:
    A phenotypically male of dicentric Y chromosome with no evidence of sex chromosomal mosaicism is reported. Staining of fluorescence in situ hybridization using Y chromosome centromere-specific DNA probe showed the presence of two bright fluorescent spots in Y chromosome. Testicular histology revealed maturation arrest at the stage of primary spermatocyte. It is suggested that structural anomaly of the Y chromosome is related to the disturbance of spermatogenesis.
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