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  • Title: [Research on heterocyclic compounds. VI. Imidazo(1,2-b)pyridazine derivatives].
    Author: Abignente E, Arena F, de Caprariis P.
    Journal: Farmaco Sci; 1977 Jun; 32(6):430-7. PubMed ID: 872922.
    Abstract:
    The preparation of a group of imidazo[1,2-b]pyridazin-2-carboxylic and -2-acetic acids is reported. The ethyl esters of these acids were prepared by reaction of some 3-aminopyridazines with ethyl bromopyruvate or 4-bromoacetoacetate. The acids were obtained by hydrolysis of the corresponding esters, and their anti-inflammatory activity was tested.
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