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  • Title: Endemic mycosis complicating human immunodeficiency virus infection.
    Author: Sarosi GA, DAvies SF.
    Journal: West J Med; 1996 Apr; 164(4):335-40. PubMed ID: 8732733.
    Abstract:
    Persons infected with the human immunodeficiency virus are prone to the development of many fungal diseases. Normal hosts with intact immunity usually recover from infection by these less-invasive fungi. In persons with compromised T-cell-mediated immunity, however, widespread dissemination from a pulmonary focus occurs. In this review, we discuss the epidemiology, clinical manifestations, diagnosis, and treatment of the three major North American mycoses, histoplasmosis, blastomycosis, and coccidioidomycosis. In most cases, amphotericin B is the initial drug of choice, followed by one of the azoles for lifelong maintenance therapy.
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