These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Is there a need for new antiarrhythmic drugs?
    Author: Roden DM.
    Journal: Arch Mal Coeur Vaiss; 1996 Feb; 89 Spec No 1():13-8. PubMed ID: 8734158.
    Abstract:
    Currently available antiarrhythmic drugs were developed at a time when the basic mechanisms underlying most arrhythmias were conjectural at best. Indeed, the molecular targets upon which drugs act to prevent (or to exacerbate) arrhythmias are only now being defined. Thus, recent advances in the treatment of patients with arrhythmias have emphasized non-pharmacologic approaches, which use new information on the pathophysiology of specific arrhythmias to deliver targeted therapies. For some arrhythmias, such as atrial fibrillation, it seems likely that drug therapy will remain an important part of treatment. With increasing cellular and molecular understanding of the determinants of normal and abnormal cardiac electrogenesis, it should be possible to develop effective and safer drugs for the treatment of cardiac arrhythmias.
    [Abstract] [Full Text] [Related] [New Search]