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Title: Canine distemper virus in Lake Baikal seals (Phoca sibirica). Author: Mamaev LV, Visser IK, Belikov SI, Denikina NN, Harder T, Goatley L, Rima B, Edginton B, Osterhaus AD, Barrett T. Journal: Vet Rec; 1996 May 04; 138(18):437-9. PubMed ID: 8735261. Abstract: The virus epizootic which resulted in significant mortality in Siberian seals (Phoca sibirica) in Lake Baikal during 1987/88 was caused by canine distemper virus. Sequence analysis of the virus glycoprotein genes revealed that it was most closely related to recent European field isolates of canine distemper virus. This paper presents evidence that the same virus continued to circulate in seals in Lake Baikal after the initial epizootic. Three out of 45 brain tissue samples collected from seals culled in the spring of 1992 were positive for canine distemper virus-specific nucleic acid by the reverse transcription/polymerase chain reaction and the sequences were closely related to that of the original virus isolated in 1988.[Abstract] [Full Text] [Related] [New Search]