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  • Title: Evaluation of risk factors for stomal recurrence after total laryngectomy.
    Author: Yotakis J, Davris S, Kontozoglou T, Adamopoulos G.
    Journal: Clin Otolaryngol Allied Sci; 1996 Apr; 21(2):135-8. PubMed ID: 8735398.
    Abstract:
    The development of a stomal recurrence after total laryngectomy is a complication with a dismal prognosis. The risk factors and mechanisms involved are still not well understood. In this review of 352 patients, 21 (6%) developed a stomal recurrence. We studied the group of 74 patients (21%) with subglottic involvement separately. There was no significant difference in the rate of stomal recurrence in those with emergency tracheostomy (23.3%) as compared with those with intra-operative tracheostomy (18.2%). Stomal recurrence was more strongly associated with subglottic involvement itself (20.3%) and T4 stage (15.3%). The findings suggest that submucosal extension and lymph node metastases are probably more important mechanisms of stomal recurrence than cancer cell implantation.
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