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  • Title: Observations of antigenic relatedness between viruses of the herpes simplex "neutroseron".
    Author: Killington RA, Randall RE, Yeo J, Honess RW, Halliburton IW, Watson DH.
    Journal: IARC Sci Publ (1971); 1978; (24 Pt 1):185-94. PubMed ID: 87364.
    Abstract:
    The antigenic relatedness of three viruses of the herpes simplex type 1 neutroseron - herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and bovine mammillitis virus (BMV) - has been examined by immune precipitation and virus neutralization tests. Many virus-specific infected-cell polypeptides were shown to possess antigenic sites shared by both HSV-1 and HSV-2. Cross-neutralization between the viruses is mediated through antibodies to at least two antigenic sites, one shared by HSV-1, HSV-2 and BMV and one shared by HSV-1 and HSV-2 but not BMV.
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