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  • Title: Medulloblastoma in children: CT and MRI findings.
    Author: Tortori-Donati P, Fondelli MP, Rossi A, Cama A, Caputo L, Andreussi L, Garré ML.
    Journal: Neuroradiology; 1996 May; 38(4):352-9. PubMed ID: 8738095.
    Abstract:
    Our purpose was to determine whether medulloblastoma (MB) shows specific neuroradiological features which may be employed in differential diagnosis from other common posterior cranial fossa tumours in childhood. Preoperative MRI was performed on 20 children with MB, and preoperative CT in 17 of them. All underwent surgery and histopathological diagnosis. There was a constant relationship between high density on CT and low signal on T1-weighted images. Signal behaviour on T2-weighted images and the degree of contrast enhancement were more variable. Most tumours arose in the midline, from the cerebellar vermis, involving the fourth ventricle, but hemisphere and extra-axial neoplasms were also seen. The combination of high density on CT and low signal on T1-weighted images is highly suggestive of MB and may assist preoperative differential diagnosis from other posterior cranial fossa tumours.
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